IVF-ICSI treatments for Sperm Donation and PGD requiring Patients:
1- How long after starting stimulation will egg collection be?
Ovulation induction may last approximately for 12 days.
2-About the monitoring during stimulation phase of treatment:
a) what monitoring normally takes place during the stimulation phase of the treatment (e.g. blood tests for oestrogen, for progesterone and scans)?
Follicle measurements and hormone levels in blood will indicate the time for oocyte aspiration.
b) What will the clinic be looking for (in the monitoring) to decide when egg collection will be?
Monitoring of ovarian response is performed by ultrasound scans and blood hormone levels. Development of follicle size is the criteria.
- c) How many eggs does the clinic expect to have at egg collection?
10-12 eggs are expected to retrieve.
3- About the egg collection:
a) Will I have a general anesthetic or sedation during the procedure?
You will have sedation during oocyte pick-up and not feel any pain.
b) What pain relief will I need/get after egg collection?
You will need mild pain killers after oocyte pick-up.
4- Is there anything we can do to improve the quality of the eggs or the sperm? (e.g. lifestyle factors or supplements)
At this moment you can not do anything to increase the quality of egg and sperm. Stop smoking if you do.
5- About the embryo transfer:
a) How many days after egg collection will this be (on average)?
Embryo transfer is done 3 to 5 days after oocyte pick-up.
b) How many cells does the clinic expect them to be by then? (grateful for your advice on blastocysts and assisted hatching)
Assited hatching is still debatable however we have laser instrument and hatching is performed in women over 35 and/ or when embryos have a thick zone. Assisted hatching is also used when the patient has a previous multiple implantation failure in the IVF cycle. Blastocyst transfer is performed in our center in cases that have more than 10 eggs.
c) How many embryos are transferred by the clinic ?
We usually transfer 2-3 embryos into the uterus
d) How does the clinic grade the embryos?
Emryo grading is performed according to number and the appearance of the cells (blastomers)
e) Under what conditions would you freeze any ‘spare’ embryos?
If spare emryos are good in shape and minister of blastomers is appropriate it means that they are worth to freeze.
6- Does the clinic recommend any additional treatment during the cycle of ICSI (e.g. low dose aspirin, IVIG, heparin etc.)
We give aspirin and corticosteroids after embryo transfer.
7-How long after embryo transfer will it be safe to fly back to the home country?
you can travel 1-2 days after embryo transfer
8-What if any medication that may be required after embryo transfer-will you prescribe for me before my return home?
We will provide all medications before you leave Cyprus
9- What are the risks (including side-effects) that we need to be aware of?
Every patient responds on the ovarian stimulation differently. Sometimes, cases may to be cancelled because of poor ovarian response or ovarian hyper stimulation.
Another main reason for canceling treatment will be none-presence of sperm in the azospermic patient after the testicular biopsy procedure ( Micro-TESE)
For Egg Donation Patients:
1) Which medications will I use for the preparation of the Endometium ?
If there is still menstrual bleeding, Lupron/Buserelin or similar medications will be used together with estrogen containing medications such as Estrofem. If there is no menstrual bleeding, then only Estrofem medications will be used.
2) How long will it take for the endometrium to be ready for the transfer and what needs to be done besides using medications ?
It takes about 13-15 days for the endometrium to be ready. The thickness must be checked under ultrasound guidance every 2-3 days in the home country.
3) What if there would be problems with the preparation of the womb ?
The cycle can be cancelled and tried another time after the reason for the problem is solved. There is no financial commitment except the deposit in such a situation. In certain cases, there may be myomas, cysts and similar infections in the woman’s uterus. Therefore an ultrasound scan of the womb is a must before the beginning of the treatment. These infections can negatively affect the success of the treatment depending on their size and location. Hysterescopy procedure is also recommended if especially there were several negative cycles before.
4) What are the natinality of the donors?
Most of the donor ladies are from Cyprus. There are also several Eastern European and Black donors available.
5) How many embryos do the egg receipient receive ?
Egg receipient receives 3 fresh embryosall of which can be transferred back to the womans’ uterus. If the couple wants to have frozen embrys, the clinic will freeze 3 embryos.
OTHER QUESTIONS :
1) Can treatments be split between England and Cyprus ?
Yes, we can direct patients to doctors in London area. Their involvement can reduce the time spent in Cyprus to only 8 days instead of 21 days for all treatments.
2) Do you do package arrangements ?
Yes, on top of the treatments, we can also arrange hotel accomodation, meals, airfares, transportation, car hire, and insurance as well through partner travel agents.
3) Does the clinic do embryo freezing and frozen embryo transfer ?
Yes, both procedures are done at the clinic.